Objectives of Programme's Learning Outcomes

• In the field of chemistry, possess highly specialised and integrated knowledge and a wide range of skills adding to those covered in the Bachelor's programme in chemistry.
• Help lead and complete a major development project, individually or in teams, related to chemistry.
• Mobilise, articulate and promote the knowledge and skills acquired.
• Manage research, development and innovation within chemistry and/or its applications.
• Understand unprecedented problems in chemistry.
• Mobilise their knowledge effectively, identify their limits, conduct methodical research and critically analyse scientifically valid information.
• Communicate clearly in the scientific domain.
• Communicate, both orally and in writing, their findings, original proposals, knowledge and underlying principles, in a clear, structured and justified manner.
• Develop and integrate a high degree of autonomy.
• Pursue their education and gain additional knowledge and new skills.
• Adapt and evolve in a new context.
• Apply high quality scientific methodology.
• Critically reflect on the impact of chemistry in general and projects to which they particularly contribute.

Learning Outcomes of UE

The main objective of this course is to provide to the students the major tools uise di the rediciton of potektail toxic effects of chemicals.  Consequently, at the end of this course, the students will be able to :

-  understand and describe the predictive approach based on structure-activity relationship (QSAR)

- Use predictive softwares (Meteor and Derek) for the prediction of the metabolism and the safety of a substance from its chemical structure

- identify the most appropriate <em>in vitro and</em><em> in vivo assays for risk assessment based on the target organ</em>

- interprete data obtained by genomics, proteomics, and metabonomics approaches applied to toxicology

- design a study protocol for preclinical toxicology evaluation

Content of UE

After a short introduction on the basic concepts in toxicology, the course will be divided into two sections:

1. <em>in silico </em><em>Models</em><em> </em>/QSAR

2. <em>in vitro </em>et <em>in vivo </em>Models (mutagenicity, developmental toxicity, major target organs)

3. Genomics, proteomics, and metabonomics approaches applied to toxcicology

Prior Experience

Not applicable

Type of Assessment for UE in Q2

• Oral Examination

Q2 UE Assessment Comments

Not applicable

Type of Assessment for UE in Q3

• Oral examination

Q3 UE Assessment Comments

Not applicable