 | Study programme 2020-2021 | Français | |
 | Predictive Toxicology | ||
Programme component of Bachelor's in Pharmacy à la Faculty of Medicine and Pharmacy |
| Students are asked to consult the ECTS course descriptions for each learning activity (AA) to know what special Covid-19 assessment methods are possibly planned for the end of Q3 |
|---|
| Code | Type | Head of UE | Department’s contact details | Teacher(s) |
|---|---|---|---|---|
| UM-B3-PHARMA-008-M | Optional UE | COLET Jean-Marie | M125 - Biologie humaine et Toxicologie |
| Language of instruction | Language of assessment | HT(*) | HTPE(*) | HTPS(*) | HR(*) | HD(*) | Credits | Weighting | Term |
|---|---|---|---|---|---|---|---|---|---|
| 0 | 0 | 0 | 0 | 0 | 3 | 3.00 |
| AA Code | Teaching Activity (AA) | HT(*) | HTPE(*) | HTPS(*) | HR(*) | HD(*) | Term | Weighting |
|---|
| Programme component | ||
|---|---|---|
 | UM-B1-PHARMA-003-M Mathematical Introduction to Life Sciences | |
| UM-B1-PHARMA-005-M Mathematics in Life Sciences | |
 | UM-B3-PHARMA-006-M General Pharmacology | |
| | UM-B3-PHARMA-007-M Introduction to Cell Pharmacology | |
Learning Outcomes of UE
The main objective of this course is to provide to the students the major tools uise di the rediciton of potektail toxic effects of chemicals. Consequently, at the end of this course, the students will be able to :
- understand and describe the predictive approach based on structure-activity relationship (QSAR)
- Use predictive softwares (Meteor and Derek) for the prediction of the metabolism and the safety of a substance from its chemical structure
- identify the most appropriate in vitro and in vivo assays for risk assessment based on the target organ
- interprete data obtained by genomics, proteomics, and metabonomics approaches applied to toxicology
- design a study protocol for preclinical toxicology evaluation
Content of UE
After a short introduction on the basic concepts in toxicology, the course will be divided into two sections:
1. in silico Models /QSAR
2. in vitro et in vivo Models (mutagenicity, developmental toxicity, major target organs)
3. Genomics, proteomics, and metabonomics approaches applied to toxcicology
Prior Experience
Not applicable
Type of Assessment for UE in Q2
- Written examination
- eTest
Q2 UE Assessment Comments
Not applicable
Type of Assessment for UE in Q3
- Written examination
- eTest
Q3 UE Assessment Comments
Not applicable