Study programme 2020-2021Français
Méthodes de ciblage moléculaire et applications biomédicales de l'imagerie moléculaire
Programme component of Master's in Biomedical Sciences à la Faculty of Medicine and Pharmacy

Students are asked to consult the ECTS course descriptions for each learning activity (AA) to know what special Covid-19 assessment methods are possibly planned for the end of Q3

CodeTypeHead of UE Department’s
contact details
UM-M1-BIOMED-026-MOptional UEBURTEA CarmenM108 - Chimie générale, organique et biomédicale
  • BURTEA Carmen

of instruction
of assessment
HT(*) HTPE(*) HTPS(*) HR(*) HD(*) CreditsWeighting Term
  • Français

AA CodeTeaching Activity (AA) HT(*) HTPE(*) HTPS(*) HR(*) HD(*) Term Weighting
M-CGOB-008Methods of targeting in molecular imaging22.50000Q1
M-CGOB-011Méthodes de ciblage en imagerie moléculaire et applications biomédicales de l'imagerie moléculaire - Travaux personnels001000Q2
Programme component

Objectives of Programme's Learning Outcomes

  • Scientific skills
    • Implement and independently carry out an experimental approach, validate a model by comparing its predications with experimental results, assess the limitations of the model's validity, and identify sources or error.
    • In response to situations and aware of the methodological limitations: - Use common techniques of biochemistry, molecular biology, cell biology, studies of tissues and organs (i.e. link a macroscopic phenomenon to microscopic processes). - Use an experimental device in a biological model, know and use the concepts and techniques of animal physiology.
    • Be familiar with biomedical science research tools, including bioinformatics tools.
    • Appropriately select measuring instruments, analyse and process the signal obtained
    • Be a responsible researcher: - Know how to base their reasoning on data obtained from scientific literature. - Know how to integrate an ethical dimension in their reasoning. - Be loyal (to the facts, to the team, and to intellectual property). - Do not tamper with results. - Do not exploit the work of others. - Demonstrate experimental rigor.
  • Professional integration skills
    • Invest their knowledge and skills in professional scenarios
    • In the digital age, be responsible for the mastery of their digital identity, and respect the rules on privacy and intellectual property
    • Be accountable for their actions and practices in decision-making regarding humans, biodiversity, the environment and society
    • Be aware of ethical issues and apply ethical codes specific to life sciences in their behaviour
    • Work independently: - Get organised, manage time and priorities, assess themself. - Master assessment methods. - Continue learning individually, prepare to educate themselves throughout life. - Demonstrate abstract thinking. - Be introduced to project management. - Show initiative.
    • Demonstrate their ability to research, analyse and synthesise: - Research, analyse, use different sources of information and materials related to biomedical sciences, format them to draw up a summarised document, produced and broadcast them on digital media. - Carry out a study, identify and raise an issue in a predefined context, build and develop an argument, interpret the data and results, develop an overview, and propose extensions. - Question themselves, think critically, debate, and defend their ideas.

Learning Outcomes of UE

The students will be familiarized with the modern methodology used to discover active pharmacological compounds, with a focus on the phage display technology which is a fundamental scientific tool of the Molecular Imaging Laboratory (Department of General, Organic and Biomedical Chemistry) of the University of Mons. The applications in the field of therapeutics and particularly in that of medical molecular imaging will be developed.

Content of UE

The course will be scheduled according to the following major plan:
- definition of biomarkers and presentation of the identification methodology;
- definition of the targeted molecular ligand;
- presentation of the high throughput screening methodology used in the discovery of the active pharmaceutical compounds;
- presentation of the methodology used to validate the active pharmaceutical compounds;
- the exigencies and advantages of the in vivo molecular imaging;
- molecular imaging of the cardiovascular system;
- molecular imaging of the nervous system;
- imaging of the liver function;
- molecular imaging of the renal function;
- cancer imaging

Prior Experience

Not applicable

Type of Assessment for UE in Q1

  • N/A

Q1 UE Assessment Comments

Pas d'application

Type of Assessment for UE in Q2

  • Written examination

Q2 UE Assessment Comments

The active participation of the students during the course will contribute to evaluation process.

Type of Assessment for UE in Q3

  • Written examination

Q3 UE Assessment Comments

Idem Q2

Type of Resit Assessment for UE in Q1 (BAB1)

  • N/A

Q1 UE Resit Assessment Comments (BAB1)

Not applicable

Type of Teaching Activity/Activities

AAType of Teaching Activity/Activities
  • Cours magistraux
  • Conférences
  • Préparations, travaux, recherches d'information

Mode of delivery

AAMode of delivery
  • Mixed
  • Mixed

Required Reading


Required Learning Resources/Tools

AARequired Learning Resources/Tools
M-CGOB-008Copies of the PowerPoint presentations are available on the Moodle platform.
M-CGOB-011Scientific publications

Recommended Reading


Recommended Learning Resources/Tools

AARecommended Learning Resources/Tools
M-CGOB-008Sans objet
M-CGOB-011Not applicable

Other Recommended Reading

AAOther Recommended Reading
M-CGOB-008- High throughput screening: the discovery of bioactive substances, Devlin JP, Ed, CRC Press, 1997.
- High-Throughput Screening in Drug Discovery, Jörg Hüser J, Mannhold R, Kubinyi H, Folkers G (editors), Wiley-VCH, 2006.
- High Throughput Screening: Methods and Protocols, Janzen WP, Humana Press Inc., U.S., 2002
- Phage display: A practical approach, Clackson T, Lowman HB, Eds, Oxford University Press Inc, New York, 2004
- Phage display in biotechnology and drug discovery, Sidhu SS, Ed, CRC Press, Taylor & Francis Group, USA, 2005.
M-CGOB-011Not applicable
(*) HT : Hours of theory - HTPE : Hours of in-class exercices - HTPS : hours of practical work - HD : HMiscellaneous time - HR : Hours of remedial classes. - Per. (Period), Y=Year, Q1=1st term et Q2=2nd term
Date de génération : 09/07/2021
20, place du Parc, B7000 Mons - Belgique
Tél: +32 (0)65 373111