Study programme 2020-2021Français
Biologie moléculaire
Programme component of Master's in Biomedical Sciences à la Faculty of Medicine and Pharmacy

Students are asked to consult the ECTS course descriptions for each learning activity (AA) to know what special Covid-19 assessment methods are possibly planned for the end of Q3

CodeTypeHead of UE Department’s
contact details
UM-M1-BIOMED-034-MOptional UEDECLEVES Anne-EmilieM122 - Biochimie métabolique et moléculaire
  • DECLEVES Anne-Emilie

of instruction
of assessment
HT(*) HTPE(*) HTPS(*) HR(*) HD(*) CreditsWeighting Term
  • Français
Français303000033.002nd term

AA CodeTeaching Activity (AA) HT(*) HTPE(*) HTPS(*) HR(*) HD(*) Term Weighting
M-BIMO-204Molecular biology3030000Q2100.00%
Programme component

Objectives of Programme's Learning Outcomes

  • Scientific skills
    • Implement and independently carry out an experimental approach, validate a model by comparing its predications with experimental results, assess the limitations of the model's validity, and identify sources or error.
    • In response to situations and aware of the methodological limitations: - Use common techniques of biochemistry, molecular biology, cell biology, studies of tissues and organs (i.e. link a macroscopic phenomenon to microscopic processes). - Use an experimental device in a biological model, know and use the concepts and techniques of animal physiology.
    • Use acquisition and data analysis software specific to biomedical sciences
    • Be familiar with biomedical science research tools, including bioinformatics tools.
    • Appropriately select measuring instruments, analyse and process the signal obtained
    • Use basic mathematical tools
    • Master the statistical tools for life sciences
    • Be a responsible researcher: - Know how to base their reasoning on data obtained from scientific literature. - Know how to integrate an ethical dimension in their reasoning. - Be loyal (to the facts, to the team, and to intellectual property). - Do not tamper with results. - Do not exploit the work of others. - Demonstrate experimental rigor.
  • Professional integration skills
    • Invest their knowledge and skills in professional scenarios
    • Network, and use digital communication and collaboration tools
    • Work in teams in different contexts including with people from different disciplines, integrate, fit in, collaborate, communicate and report
    • Be aware of ethical issues and apply ethical codes specific to life sciences in their behaviour
    • Be introduced to the process of production, distribution and exploitation of knowledge
    • Work independently: - Get organised, manage time and priorities, assess themself. - Master assessment methods. - Continue learning individually, prepare to educate themselves throughout life. - Demonstrate abstract thinking. - Be introduced to project management. - Show initiative.
    • Demonstrate their ability to research, analyse and synthesise: - Research, analyse, use different sources of information and materials related to biomedical sciences, format them to draw up a summarised document, produced and broadcast them on digital media. - Carry out a study, identify and raise an issue in a predefined context, build and develop an argument, interpret the data and results, develop an overview, and propose extensions. - Question themselves, think critically, debate, and defend their ideas.
    • Master written and oral scientific expression. Be independent in writing and show that they can communicate their thoughts, reason and organise their knowledge
    • Make a presentation illustrating arguments adapted to the object, the circumstances and the public: speak in public
    • Master scientific English: - Present scientific results, orally and in writing. - Answer scientific questions in English

Learning Outcomes of UE

Students will complete their knowledge on the gene expression as well as on protein functions. Therefore, at the end of the lecture, the basic principles associated with the genetic material will be acquired. The lecture will discuss new concepts and advanced methodologies in the area of molecular biology, including the new generation sequencing. Theoretical concepts will help the students to extract information from public databases (internet) and understand published scientific results. During practical work in laboratory, they will perform several techniques such as cloning and manipulation of recombinant DNA (PCR, cloning, determination and computer analysis of sequences).

Content of UE

After a review of the structure of DNA, its modifications and gene expression ( replication , transcription, translation and compensation ), the course will cover the main techniques related to molecular biology , the genetic engineering ( electrophoresis of DNA , DNA cloning , restriction enzyme , ...) to transgenesis ; but also more modern techniques derived from the discovery of the human genome as microarray DNA , or pharmacogenomics techniques that lead us towards personalized medicine . The exercises and practical work will illustrate the theoretical lecture.   The student will learn (1) how to understand and perform an experimental protocol, (2) how to analyse data and look for information on internet, (3) how to set up the best strategy to answer a scientific question. Moreover, during a team work entitled "Du gène à la physiopathologie: une approche intégrée ", the students will have reminders of the specific biochemistry notions to realize the work. Demonstration of the use of different databases requisite to realize the work. Group exercise on a specific case from a gene acronym and a pathology.

Prior Experience

Not applicable

Type of Assessment for UE in Q2

  • Written examination
  • Practical test
  • Graded tests
  • eTest

Q2 UE Assessment Comments

Lecture = open-ended questions and/or MCQ and/or right or false
Practical work = evaluated report, scored exercises + final test
Weighting = 10 % of total score
Section « Du gène à la physiopathologie : une approche intégrée » = presentation of a work (article) Weighting = 10 % of total score  

Type of Assessment for UE in Q3

  • Written examination

Q3 UE Assessment Comments

  The Q3 evaluation will be based on the lecture = MCQ and/or open-ended questions and/or right or false. The score reached in Q2 regarding eTest and practical work will be added in Q3 fo a weighting of 20%.

Type of Teaching Activity/Activities

AAType of Teaching Activity/Activities
  • Cours magistraux
  • Travaux pratiques
  • Travaux de laboratoire
  • Projet sur ordinateur
  • Etudes de cas

Mode of delivery

AAMode of delivery
  • Face to face
  • Mixed

Required Reading


Required Learning Resources/Tools

AARequired Learning Resources/Tools
M-BIMO-204The lecture will be illustrated by a slide show and Power Point animations . The slide of each course will be available to students via the Moodle platform .  

Recommended Reading


Recommended Learning Resources/Tools

AARecommended Learning Resources/Tools
M-BIMO-204reference book: J. Etienne 'Biochimie génétique - Biologie moléculaire' Masson

Other Recommended Reading

AAOther Recommended Reading

Grade Deferrals of AAs from one year to the next

AAGrade Deferrals of AAs from one year to the next
(*) HT : Hours of theory - HTPE : Hours of in-class exercices - HTPS : hours of practical work - HD : HMiscellaneous time - HR : Hours of remedial classes. - Per. (Period), Y=Year, Q1=1st term et Q2=2nd term
Date de génération : 09/07/2021
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