Objectives of Programme's Learning Outcomes

• Understand, describe, analyse and prioritise biological phenomena
• Understand basic scientific knowledge and be able to use it
• Problem-solve
• Understand the expression of biological realities in absolute or relative terms, the orders of magnitude, proportions and probability
• Abstract, understand and apply mathematical translations of the main laws and biological phenomena
• Understand and use different graphical representations of numerical values and their relationships
• Perceive spatial distribution, and understand two- and three-dimensional representations and interconvert them
• Understand the chronology of a phenomenon and master the time scales and their representations
• Control the molecular, morphological and functional approaches of normal and pathological conditions
• Understand the learning of physiological and pharmacological reasoning
• Understand experimental protocols in the biomedical domain
• Integrate concepts from different approaches/disciplines in a complex biomedical problem
• Explain how molecular, morphological and functional modifications constitute pathological states and vice versa
• Develop reasoning skills
• Understand and apply the basic principles of reasoning (obtaining data, analysis, synthesis, comparison, the rule of three, syllogism, analogy, Boolean logic, etc.)
• Work with efficiency / accuracy / precision
• Present a hypothesis and hypothetical-deductive reasoning
• Develop critical thinking, test and monitor conclusions understanding the domain of validity, and explore alternative hypotheses
• Manage doubt and uncertainty
• Demonstrate developed interpersonal skills
• Use a rich vocabulary linking concepts and words accurately
• Adapt lexical and syntactic choices in communication register (everyday language, medical language or scientific terminology)
• Summarise, explain, and argue
• Work in a team
• Share knowledge and information
• Manage resources
• Manage time
• Prioritise
• Use basic IT and bibliographic resources.
• Manage their studies
• Locate scientific information efficiently
• Compare different sources of information
• Read, interpret, and critique a scientific article
• Self-assess and give feedback
• Be open to research and demonstrate scientific curiosity

Learning Outcomes of UE

Biochemistry is at the frontier of biological science and chemical science. Indeed, biochemistry seeks to understand the chemical basis for all life processes. It is therefore a key discipline in medical, biomedical and pharmaceutical research. Indeed, biochemistry helps to understand biological processes, allows to identify the mechanisms involved in disease and especially allows to better define a treatment. The purpose of this course will be to acquire the basic knowledge of biochemical functions (molecule structure, enzymology, bioenergetic). Knowledges that will then be used to understand and interpret biochemical processes. At the end of this course, students will be able to: ·       understand the role of the 4 main classes of small organic molecules of the cells (aa, monosaccharides, nucleotides and lipids) in the main biochemical pathways; ·       understand the acid-base chemistry and the importance of water in the biochemical processes; ·       interpret the impact of changes in pH on ionizable groups of a peptide or a protein; ·       understand the concept that the structure of a given biomolecule is directly related to its function; ·       understand the role and the regulation of enzymes in biochemical reactions; ·       understand the energetics of life and associate the notion of bio-energy to the metabolic pathways; ·             understand the mecanisms of metabolic regulation ; ·       address without difficulties the course of metabolic biochemistry
 

UE Content: description and pedagogical relevance

The lecture will be st up in three main parts: I. Reminder of the 4 main classes of small organic molecules of the cells, the water structure, pH and the acid-base chemistry II. Structures and functions of the proteins and enzymes III. The energetics of life, and metabolism and regulation ==> The lecture (face-to-face) will be associated with practical works (supervised work, exercices and e-learning)
 

Prior Experience

Not applicable