Objectives of Programme's Learning Outcomes

• Skill 1: Have acquired highly specialised and integrated knowledge and broad skills inbiological sciences, adding to those covered in the Bachelor's programme in biological sciences.
• Skill 2: Have acquired professional skills relating to the degree.
• Apply, mobilise, articulate and promote the knowledge and skills acquired in order to contribute to the achievement of research project in biology.
• Skill 4: Master communication techniques.
• Communicate, in English both orally and in writing, their findings, original proposals, knowledge and underlying principles, in a clear, structured and justified manner.
• Skill 5: Develop and integrate a high degree of autonomy.
• Aquire new knowledge independently.
• Skill 6: Apply scientific methodology.
• Critically reflect on the impact of their discipline in general, and on the contribution to projects.

Learning Outcomes of UE

The main objective of this class is to describe the major alternative approaches, in vitro models and 'omics' tools, to predict the potential toxic effects of chemicals.  Consequently, at the end of this course, the students will be able to :

- identify the most appropriate in vitro and in vivo assays to assess the mutagneic risk of chemicals

- interprete data obtained by the Ames assay

- design a study protocol for preclinical toxicology evaluation

UE Content: description and pedagogical relevance

This class will focus on in vitro et in vivo Models (mutagenicity), as well as genomics, proteomics, and metabonomics approaches applied to toxcicology

Prior Experience

Fundamentals in general toxicology
Part I of predictive toxicology class