Objectives of Programme's Learning Outcomes

• Have acquired professional skills in relation to the objective defining the degree.
• Specialise in at least one sub-domain of chemistry.
• In the field of chemistry, possess highly specialised and integrated knowledge and a wide range of skills adding to those covered in the Bachelor's programme in chemistry.
• Help lead and complete a major development project, individually or in teams, related to chemistry.
• Mobilise, articulate and promote the knowledge and skills acquired.
• Manage research, development and innovation within chemistry and/or its applications.
• Possibly propose innovative solutions to targeted problems, which also requires attentiveness and mutual respect, as well as argue and establish constructive debates.
• Communicate clearly in the scientific domain.
• Communicate, both orally and in writing, their findings, original proposals, knowledge and underlying principles, in a clear, structured and justified manner.
• Adapt their communication to a variety of audiences.
• Develop and integrate a high degree of autonomy.
• Aquire new knowledge independently.
• Pursue further training and develop new skills independently.
• Apply high quality scientific methodology.
• Critically reflect on the impact of chemistry in general and projects to which they particularly contribute.

Learning Outcomes of UE

The course of nanotechnology aims to detail the utility of polymeric materials in the galenic chemistry. During our lectures, questions such as: "Why polymer materials are usefull ? How can we trap drugs? How medecines are working?" will be discussed.

UE Content: description and pedagogical relevance

I.Introduction   I.1.  Terminology   a.  Controlled release   b.  Prolonged-Sustained release   c.  Drug targeting   I.2.  Objectives of controlled release drugs II.Factors Influencing the Design and Operation of Controlled / Extended-Release Drugs III. Physicochemical properties of the drug substances influencing the design and the efficacy of the dosage form       a. Partition Coefficient       b. Degree of ionization       c. Molar mass and molecular volume       d. Solubility        e. Stability        f. Protein binding IV.Biological properties of the drug substance influencing the design and efficacy of a controlled / prolonged release drug   IV.1.  Absorption   IV.2.  Distribution   IV.3.  Metabolisation   IV.4.  Elimination V.Controlled release forms   a.  Twox classes   b.  Polymers employed   b.1.  Glossary of polymer used   b.1.1.  Natural polymers   b.1.2.  Synthetic polymers               A.  Carbonated polymers               B.  Polymers with heteroatoms   c.  Microencapsulation   c.1.  Application of micro/nanoencapsulation   c.2.  Incorporation of drugs   -  Chemical conjugation (prodrog)   -  Physical entrapment   -  Polyionic complexation   d.  Nanovectorisation of drugs and tumor targeting   d.1.  Definition and illustrations   d.2.  First generation vectors   d.3.  Second generation vectors   d.4.  Third generation vectors   d.5.  Tumor targeting  

Prior Experience

Not applicable